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By now you’ve probably learned a few things about large B-cell lymphoma.

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Like how it can resist or even return after treatment. 

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If that happens, there’s a scientific advancement that could help. It's called CAR T-cell therapy.

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And it starts with a disease fighter already inside your body.
Your T cells. 

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T cells are a type of white blood cell—a part of your immune system.

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And they patrol your body to help fight bacteria, viruses, and even cancer.

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But sometimes, they need a hand. Because your T cells can have trouble recognizing 

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the cancerous B cells in lymphoma, they can’t destroy them.

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That’s where CAR T-cell therapy comes in. First, your T cells are removed from your blood.

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Then, in a lab, they’re modified. A new molecule, called 

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a chimeric antigen receptor (or CAR), is added to their surface.

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This turns them from T cells…into CAR T Cells.

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Then, through an infusion, millions of these CAR T cells are put back into your body

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Where, with their new receptor, they can recognize and destroy B cells,

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including the cancerous ones.

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So now you know about CAR T-cell therapy. But it’s time to know if it’s right for you.

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Ask your doctor about a CAR T-cell therapy called YESCARTA.

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YESCARTA is a prescription medicine used to treat large B-cell lymphoma when your first 

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treatment did not work or your cancer returned within a year of first treatment,

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OR when at least two kinds of treatment have failed to control your cancer.

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With YESCARTA, the power to fight back against cancer starts with the fighter within you.

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Keep exploring this site to learn more about how YESCARTA can help. 

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But first, please listen to Important Safety Information about YESCARTA.

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YESCARTA is a prescription medicine used to treat large B-cell lymphoma

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a type of non-Hodgkin lymphoma, when your first treatment did not work

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or your cancer returned within a year of first treatment

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OR when at least two kinds of treatment have failed to control your cancer.

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YESCARTA is different than other cancer medicines because 

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it is made from your own white blood cells,

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which have been modified to recognize and attack your lymphoma cells.

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YESCARTA may cause side effects that are life-threatening and can lead to death. Call or see

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your healthcare provider or get emergency help right away if you get any of the following:

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Fever,Difficulty breathing,Chills or shaking chills,Confusion
,Dizziness or lightheadedness, Severe nausea, vomiting, or diarrhea

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Fast or irregular heartbeat, Severe fatigue or weakness. It is important to tell your healthcare 

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provider that you received YESCARTA and to show them your YESCARTA Patient Wallet Card. 

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Your healthcare provider may give you other medicines to treat your side effects.

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Before getting YESCARTA, tell your healthcare provider about

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all your medical problems, including if you have or have had:

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Neurologic problems (such as seizures, stroke, or memory loss) Lung or 

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breathing problems, Heart problems, Liver problems, Kidney problems, A recent or active infection

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Tell your healthcare provider about all the medications you take, including

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prescription and over-the-counter medicines, vitamins, and herbal supplements.

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Since YESCARTA is made from your own white blood cells, your blood will be collected

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by a process called “leukapheresis”, which will concentrate your white blood cells.

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Your blood cells will be sent to a manufacturing center to make your YESCARTA.

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Before you get YESCARTA, you will get 3 days of chemotherapy to prepare your body.

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When your YESCARTA is ready, your healthcare provider will give it to you

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through a catheter placed into your vein (intravenous infusion).

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The infusion usually takes less than 30 minutes.

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You will be monitored where you received your treatment daily for at least

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7 days after the infusion. You should plan to stay close to the location 

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where you received your treatment for at least 4 weeks after getting YESCARTA.

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Your healthcare provider will help you with any side effects that may occur.

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You may be hospitalized for side effects and your healthcare provider will discharge you

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if your side effects are under control, and it is safe for you to leave the hospital.

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Your healthcare provider will want to do blood tests to follow your progress. 

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It is important that you do have your blood tested.

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If you miss an appointment, call your healthcare provider as soon as possible to reschedule.

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Do not drive, operate heavy machinery, or do other dangerous things for

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8 weeks after you get YESCARTA because the treatment can cause sleepiness, confusion,

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weakness, and temporary memory and coordination problems.

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Do not donate blood, organs, tissues, or cells for transplantation.

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The most common side effects of YESCARTA include:

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Fever, Low white blood cells (which can occur with a fever), Low red blood cells,

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Low blood pressure (dizziness or lightheadedness, 
headache, feeling tired, short of breath)

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Fast heartbeat, Confusion, Difficulty speaking or slurred speech, 

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Nausea, Diarrhea. These are not all the possible side effects of YESCARTA.

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Call your healthcare provider about any side effects that concern you.

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You are encouraged to report negative side effects of prescription drugs to the FDA.

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Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please see link located below this video to read 
the Important Facts, including IMPORTANT WARNINGS.