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YESCARTA is a prescription medicine used to treat large B-cell lymphoma, a type of non-Hodgkin lymphoma, when your first treatment did not work or your cancer returned within a year of first treatment, OR when at least two kinds of treatment have failed to control your cancer. YESCARTA is different than other cancer medicines because it is made from your own white blood cells, which have been modified to recognize and attack your lymphoma cells Read Less

How YESCARTA can help

If one or more treatments didn’t control your large B-cell lymphoma (LBCL), YESCARTA could give you another chance against cancer. And it’s already helping people just like you.

How many treatments have you had for LBCL?

Click below to see what YESCARTA could do for you.

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One treatment didn’t work or your cancer
returned within a year of first treatment

Two or more treatments
didn't control your cancer

YESCARTA AFTER 1 TREATMENT DIDN'T WORK OR YOUR CANCER RETURNED WITHIN A YEAR OF FIRST TREATMENT

A single infusion.
A second chance to control cancer.

If chemotherapy didn’t work, you need another treatment that can get your cancer under control. And that treatment could be YESCARTA. Take a closer look:

YESCARTA was studied in a clinical trial of 359 adult patients with large B-cell lymphoma when their first treatment did not work or the cancer returned within a year of first treatment.

180

patients were assigned to get YESCARTA

179

patients were assigned to get standard therapy*

*Standard therapy was defined as chemotherapy followed by high-dose therapy and autologous stem cell transplant.

With YESCARTA, patients had improved results:

4x LONGER without an event with YESCARTA

8.3 months without
an event for half of patients on
YESCARTA

2.0 months without
an event for half of patients
on standard therapy

An event is starting a new lymphoma treatment, cancer getting worse, or death.

60% REDUCED RISK with YESCARTA

The risk of needing to start a new lymphoma treatment, cancer getting worse, or death dropped by 60% vs standard therapy.

What to expect when on YESCARTA

Learn how YESCARTA is given to patients and see what to expect during your treatment journey.

See what to expect

Get the most out of your next doctor’s visit

Considering YESCARTA? This list of useful discussion topics will help guide a productive conversation with your oncologist.

Download now

YESCARTA after 2 or more treatments failed to control your cancer

A single infusion.
A chance at lasting remission.

If you’ve had 2 or more treatments for large B-cell lymphoma, YESCARTA can help put your cancer in complete and lasting remission. Take a closer look:

YESCARTA was studied in 101 patients with large B-cell lymphoma whose cancer wasn't controlled after being treated:

72%

achieved partial or complete
remission with YESCARTA

51%

of patients achieved complete remission,
seeing a disappearance of all signs of cancer.
This does not always mean the cancer has been cured

21%

of patients achieved partial remission,
experiencing a decrease in the amount of cancer within the body

Most of the patients who achieved a complete remission were still in a complete remission 2 years after treatment.

Remission is possible in as little as
1 month after treatment

In the YESCARTA clinical study, half of patients with large B-cell lymphoma
achieved remission in as little as 0.9 months (range: 0.8–6.2 months).

Real YESCARTA patients. Real stories of remission.

The following patients’ stories might sound familiar. Just like you, each of them had multiple treatments that couldn’t control their large B-cell lymphoma. Watch how they found lasting remission with YESCARTA.

Please see the Important Facts, including IMPORTANT WARNINGS.

Meet Gary

In 2016, Gary was beginning his new life as a retiree. That’s when he was diagnosed with large B-cell lymphoma. After radiation and several lines of chemotherapy didn’t control his cancer, his oncologist told him about YESCARTA.

Nearly eight weeks after my infusion with YESCARTA, my PET scan showed the cancer was gone.

Gary
A real patient who received YESCARTA after multiple treatments did not control their cancer. Results and side effects may vary. Featured patients are sponsored by Kite.

Please see the Important Facts, including IMPORTANT WARNINGS.

Meet Sharon

Sharon was blindsided by a diagnosis of large B-cell lymphoma. She needed to know she would have another option if treatments failed her. YESCARTA gave her another path forward.

I’m proof that there’s hope.

Sharon
A real patient who received YESCARTA after multiple treatments did not control their cancer. Results and side effects may vary. Featured patients are sponsored by Kite.

What to expect when on YESCARTA

Learn how YESCARTA is given to patients and see what to expect during your treatment journey.

See what to expect

Get the most out of your next doctor’s visit

Considering YESCARTA? This list of useful discussion topics will help guide a productive conversation with your oncologist.

Download now
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IMPORTANT SAFETY INFORMATION
What is the most important information I should know about YESCARTA?

YESCARTA may cause side effects that are life-threatening and can lead to death. Call or see your healthcare provider or get emergency help right away if you get any of the following:

  • Fever (100.4°F/38°C or higher)
  • Difficulty breathing
  • Chills or shaking chills
  • Confusion
  • Dizziness or lightheadedness
  • Severe nausea, vomiting, or diarrhea
  • Fast or irregular heartbeat
  • Severe fatigue or weakness

It is important to tell your healthcare provider that you received YESCARTA and to show them your YESCARTA Patient Wallet Card. Your healthcare provider may give you other medicines to treat your side effects.

Before getting YESCARTA, tell your healthcare provider about all your medical problems, including if you have or have had:

  • Neurologic problems (such as seizures, stroke, or memory loss)
  • Lung or breathing problems
  • Heart problems
  • Liver problems
  • Kidney problems
  • A recent or active infection

Tell your healthcare provider about all the medications you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How will I receive YESCARTA?

  • Since YESCARTA is made from your own white blood cells, your blood will be collected by a process called “leukapheresis” (loo-kah-fur-ee-sis), which will concentrate your white blood cells.
  • Your blood cells will be sent to a manufacturing center to make your YESCARTA.
  • Before you get YESCARTA, you will get 3 days of chemotherapy to prepare your body.
  • When your YESCARTA is ready, your healthcare provider will give it to you through a catheter placed into your vein (intravenous infusion). The infusion usually takes less than 30 minutes.
  • You will be monitored where you received your treatment daily for at least 7 days after the infusion.
  • You should plan to stay close to the location where you received your treatment for at least 4 weeks after getting YESCARTA. Your healthcare provider will help you with any side effects that may occur.
  • You may be hospitalized for side effects and your healthcare provider will discharge you if your side effects are under control, and it is safe for you to leave the hospital.
  • Your healthcare provider will want to do blood tests to follow your progress. It is important that you do have your blood tested. If you miss an appointment, call your healthcare provider as soon as possible to reschedule.

What should I avoid after receiving YESCARTA?

  • Do not drive, operate heavy machinery, or do other dangerous things for 8 weeks after you get YESCARTA because the treatment can cause sleepiness, confusion, weakness, and temporary memory and coordination problems.
  • Do not donate blood, organs, tissues, or cells for transplantation.

What are the possible or reasonably likely side effects of YESCARTA?

The most common side effects of YESCARTA include:

  • Fever (100.4°F/38°C or higher)
  • Low white blood cells (can occur with a fever)
  • Low red blood cells
  • Low blood pressure (dizziness or lightheadedness, headache, feeling tired, short of breath)
  • Fast heartbeat
  • Confusion
  • Difficulty speaking or slurred speech
  • Nausea
  • Diarrhea
 

These are not all the possible side effects of YESCARTA. Call your healthcare provider about any side effects that concern you. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.

Please see the Important Facts, including IMPORTANT WARNINGS.

APPROVED USE

YESCARTA is a prescription medicine used to treat large B-cell lymphoma, a type of non-Hodgkin lymphoma, when your first treatment did not work or your cancer returned within a year of first treatment, OR when at least two kinds of treatment have failed to control your cancer. YESCARTA is different than other cancer medicines because it is made from your own white blood cells, which have been modified to recognize and attack your lymphoma cells.